Quatrefolic® from Gnosis is a new generation of folic acid. It represents a breakthrough in folate supplementation with regard to an active, stable, and highly bioavailable form when compared to folic acid and the methyl derivative folate. Quatrefolic® provides folate in the (6S)-5-methyltetrahydrofolate form which is easily utilized and stored in the body. Quatrefolic® uses a glucosamine salt which has been proven in both human animal studies to have greater bioavailability over calcium salt versions.